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Below is the complete list of keyboard shortcuts for Cadmium. On Mac, substitute Cmd for Ctrl.

Playback & Navigation

ActionShortcut
Play/pauseEnter
Next/previous unique frameLeft/Right Arrow
Next/previous single frameShift + Left/Right Arrow
Change active layerCtrl + Up/Down Arrow or Shift + Up/Down Arrow
Hide/show timelineT

Canvas

ActionShortcut
Hand tool (pan)Space (hold)
Zoom toolZ (+ Alt to zoom out)
Zoom in/outMiddle mouse scroll or right-click drag

Selection

ActionShortcut
Select all frames on current layerCtrl + A
Deselect frames on all layersCtrl + D
Delete frameDelete
Toggle reference frameRight-click on frame, or diamond button next to layer name

Drawing Tools

ActionShortcut
Pen toolB
Toggle pen erase/draw modeCtrl + B or hold Alt while drawing
Adjust pen sizeCtrl + right-click drag (while pen is selected)
EraserE
Fill toolF
Fill tool mode toggleD or Alt/Option
Eyedropper toolI (or Shift while pen/fill tool is selected)

Color

ActionShortcut
Color wheelC
Toggle active colorX

System

ActionShortcut
UndoCtrl + Z
RedoCtrl + Shift + Z
Force reloadCtrl + Shift + R
Keyboard shortcuts are not customizable at this time.